Meet Our Leadership Teams

Silvana is an Assistant Professor of Biochemistry at Stanford. Her research laboratory aims to understand the molecular pathways that drive the development of Alzheimer’s disease using next-generation functional genomics, with the long-term goal of developing rationally targeted therapeutics for neurodegenerative disorders. She received her Ph.D. in Neuroscience from MIT. Silvana’s pioneering work on tools to directly perturb the transcriptomic landscape of the cell using CRISPR has been recognized by her faculty appointment as a Chan Zuckerberg Biohub Investigator and Hanna Gray Fellow of the Howard Hughes Medical Institute.

Patrick Hsu is Co-Founder of the Arc Institute and Assistant Professor of Pathology at Stanford University. The Hsu lab works at the intersection of biology and machine learning to develop technologies for biological design, with recent contributions including the Evo series of genome foundation models and the first universally programmable DNA recombinases. Patrick received A.M. and Ph.D. degrees from Harvard University and the Broad Institute of MIT and Harvard, where he was an early pioneer of CRISPR-Cas9 technologies for genome editing. His research has been recognized by awards from the New York Times, The Atlantic, Forbes, MIT Technology Review, Rainwater Foundation, and Amgen.

Patrick Collison is a co-founder of the Arc Institute, a biomedical research institute that is dedicated to pioneering a new model for research. In partnership with Stanford, UCSF and UC Berkeley, Patrick, Silvana, and Patrick Hsu hope that by providing no strings attached, long term funding, Arc will bring together and enable ambitious and passionate biomedical investigators to study and address human complex diseases. Patrick's primary role is chief executive officer and cofounder of Stripe, a technology company that builds economic infrastructure for the internet. With the goal of making online payments simpler and more accessible, Patrick and his brother John started Stripe in 2010. Today, Stripe powers millions of online businesses around the world.