Welcome to the Thaiss lab!

We are a team of biologists, physicians, and computer scientists who jointly tackle the mysteries of human disease.

Research Focus

Body-brain communication

We investigate the core principles of bidirectional communication between the body and the brain, with a particular focus on interactions between the immune, metabolic, and nervous systems in physiology and disease.

Environmental and lifestyle impacts on disease

We aim to decipher the mechanistic basis of how environmental and lifestyle factors, such as diet, exercise, sleep, stress, infections, xenobiotics, temperature, social interactions, and technology interact with the human body.

The biology of aging

We explore new elements of the biology of aging, and how they influence an individual's propensity for the development of multifactorial diseases, such as neurodegeneration, cancer, cardiovascular disease, and chronic inflammatory disease.

Publications

β-Hydroxybutyrate suppresses colorectal cancer

Oxana Dmitrieva-Posocco, Andrea C. Wong, Patrick Lundgren, Aleksandra M. Golos, Hélène C. Descamps, Lenka Dohnalová, Zvi Cramer, Yuhua Tian, Brian Yueh, Onur Eskiocak, Gabor Egervari, Yemin Lan, Jinping Liu, Jiaxin Fan, Jihee Kim, Bhoomi Madhu, Kai Markus Schneider, Svetlana Khoziainova, Natalia Andreeva, Qiaohong Wang, Ning Li, Emma E. Furth, Will Bailis, Judith R. Kelsen, Kathryn E. Hamilton, Klaus H. Kaestner, Shelley L. Berger, Jonathan A. Epstein, Rajan Jain, Mingyao Li, Semir Beyaz, Christopher J. Lengner, Bryson W. Katona, Sergei I. Grivennikov, Christoph A. Thaiss, Maayan Levy

NatureApril 2022

Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner

Diego Adhemar Jaitin, Lorenz Adlung, Christoph A. Thaiss, Assaf Weiner, Baoguo Li, Hélène Descamps, Patrick Lundgren, Camille Bleriot, Zhaoyuan Liu, Aleksandra Deczkowska, Hadas Keren-Shaul, Eyal David, Niv Zmora, Shai Meron Eldar, Nir Lubezky, Oren Shibolet, David A. Hill, Mitchell A. Lazar, Marco Colonna, Florent Ginhoux, Hagit Shapiro, Eran Elinav, Ido Amit

CellJuly 2019

All Publications

Team

Christoph Thaiss
Core Investigator

Christoph Thaiss

Christoph A. Thaiss is an Assistant Professor of Pathology at Stanford University. His lab studies how interactions between environment, body, and brain impact physiology and disease over the lifespan. Christoph received his undergraduate training from the University of Bonn, Yale University, ETH Zurich, and the Broad Institute of MIT and Harvard. Following his Ph.D. studies at the Weizmann Institute of Science, he joined the faculty at the University of Pennsylvania. Among the recognitions he has received for his work are an NIH Director’s New Innovator Award, an NIDDK Catalyst Award, a Pew Biomedical Scholars Award, the Science & SciLifeLab Grand Prize for a Young Scientist, the Agilent Early Career Professor Award, a McKnight Brain Research Foundation Innovator Award, and a Burroughs Wellcome Fund Investigator in the Pathogenesis of Infectious Disease Award.

Current Members

Monika Tetlak
Lab Manager

Monika Tetlak

Iboro Umana
Gastroenterology Fellow

Iboro Umana

Maria Sacta
Allergy/Immunology Fellow

Maria Sacta

Megan Liou
Postdoctoral Fellow

Megan Liou

Alexis Cowan
Postdoctoral Fellow

Alexis Cowan

Giulia Uhr
Postdoctoral Fellow

Giulia Uhr

Andrea Salvador
Postdoctoral Fellow

Andrea Salvador

Lev Litichevskiy
MD/PhD Student

Lev Litichevskiy

Tim Cox
MD/PhD Student

Tim Cox

Prateek Sharma
MD/PhD Student

Prateek Sharma

Lenka Dohnalová
PhD Student

Lenka Dohnalová

Niklas Blank
PhD Student

Niklas Blank

Alana McSween
PhD Student

Alana McSween

Molly Weiner
PhD Student

Molly Weiner

Sydney Mason
PhD Student

Sydney Mason

Ilona Golynker
PhD Student

Ilona Golynker

Sarah Köhler
MD Student

Sarah Köhler

Emma Loeffler
MD Student

Emma Loeffler

Yixuan (Erica) Zhu
Master Student

Yixuan (Erica) Zhu

Madeleine Sleeman
Research Specialist

Madeleine Sleeman

Junny Kim
Undergraduate Researcher

Junny Kim

Maya Considine
Undergraduate Researcher

Maya Considine

Vasuprada Shandar
Undergraduate Researcher

Vasuprada Shandar

Ana Glassman
Undergraduate Researcher

Ana Glassman

Janine Haros
Undergraduate Researcher

Janine Haros

Shaan Patel
Undergraduate Researcher

Shaan Patel

Contact Us

We are looking for students and postdocs across different disciplines of biology, medicine, and computer science to support our basic and translational research. If you are interested in joining our journey, please contact us at christoph.thaiss@arcinstitute.org.

Address

Arc Institute
3181 Porter Dr
Palo Alto, CA 94304
info@arcinstitute.org
Arc Institute Location