Arc News

Arc Institute continues its work to generate and share large-scale, high-quality datasets of cell state before and after chemical or genetic perturbations to enable “virtual cell” models and other innovations. Two months after launching the Arc Virtual Cell Atlas comprising over 300 million cells, the initiative is now benefiting from new partnerships with 10x Genomics and Ultima Genomics, industry leaders in advanced tools that make collecting single cell data faster, more scalable, and more affordable for scientists working to improve human health.

Arc Institute’s 7th Core Investigator, Christoph Thaiss, officially arrived in January, moving cross-country from the University of Pennsylvania, where he was investigating how interactions between the environment, body, and brain impact physiology and disease over the lifespan.

Arc Institute today launched the Arc Virtual Cell Atlas, a growing resource for computation-ready single-cell measurements, starting with data from over 300 million cells. The initial release of the Atlas is Arc’s first step toward assembling, curating, and generating large-scale cellular data to fuel new insights from AI-driven biological discovery.

300 million single cell atlas now accessible to the scientific community comprised of Tahoe's Tahoe-100M, mapping 60,000 drug-cell interactions, and Arc’s AI-curated scBaseCount 200 million cell dataset generated using Tahoe’s Mosaic platform, Tahoe-100M leveraged Parse Biosciences’ GigaLab for single cell sample preparation and Ultima Genomics for sequencing.

Arc’s biology and machine learning researchers are working with NVIDIA’s engineers to scale the potential of AI models to design, predict, and understand biology. This partnership will build on Arc’s previous work with the Evo model, which is capable of both prediction and design at the level of DNA and across RNA and proteins in single-celled organisms.

Today, Arc Institute, the scientific research organization pioneering new models for scientific discovery and translation, is announcing the creation of its Scientific Advisory Board and its first two Scientific Advisors, as well as the appointment of two new members to the Arc Board of Directors.

Using a novel bispecific guide RNA, the bridge recombinase mechanism enables modular and programmable DNA insertion, excision, and inversion in bacteria.

Today, Arc Institute, the scientific research organization pioneering new models for scientific discovery and translation, is announcing the selection of its new cohort of fully funded Core Investigators and first Science Fellow, along with its first Innovation Investigators and Ignite Award Recipients.