Created by the labs of Brian Hie, Arc Innovation Investigator and Stanford Assistant Professor of Chemical Engineering, and Patrick Hsu, Arc Core Investigator and UC Berkeley Assistant Professor of Bioengineering, Evo was first introduced in a preprint earlier this year and has now been published in Science. Since the preprint was posted, the researchers have used Evo to design a functional CRISPR system unknown in nature, showing how this deeper understanding of biological sequences can yield new molecular tools.

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