Nature Cancer
Goodarzi Lab
A sense-antisense RNA interaction promotes breast cancer metastasis via regulation of NQO1 expression
Here we profiled antisense RNAs in the MDA-MB-231 breast cancer cell line and its highly lung metastatic derivative. We identified one antisense RNA that drives cancer progression by upregulating the redox enzyme NADPH quinone dehydrogenase 1 (NQO1), and named it NQO1-AS.