Core Facilities

Palo Alto, CA

Scientist/Sr. Scientist, Molecular Technology Development, Hsu & Konermann Lab

Core Laboratories

Information Technology Manager

Infrastructure Engineering Manager

Laboratory Operations Manager

People Team Coordinator

Scientific Recruiting Advisor

Operations

Associate Director/Director of Bioinformatics

Associate Director, Functional Genomics

Director/Sr Director, Cellular Models Center

Scientist/Sr. Scientist, Functional Genomics, Genome Engineering Technology Center

Technology Centers

No Department

&lt;p&gt;&lt;strong&gt;About Arc Institute&amp;nbsp;&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;The Arc Institute is a new scientific institution that conducts curiosity-driven basic science and technology development to understand and treat complex human diseases. Headquartered in Palo Alto, California, Arc is an independent research organization founded on the belief that many important research programs will be enabled by new institutional models. Arc operates in partnership with Stanford University, UCSF, and UC Berkeley.&amp;nbsp;&lt;/p&gt;
&lt;p&gt;While the prevailing university research model has yielded many tremendous successes, we believe in the importance of institutional experimentation as a way to make progress. These include:&amp;nbsp;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Funding: Arc will fully fund Core Investigator’s (PI’s) research groups, liberating scientists from the typical constraints of project-based external grants.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Technology: Biomedical research has become increasingly dependent on complex tooling. Arc Technology Centers develop, optimize and deploy rapidly advancing experimental and computational technologies in collaboration with Core Investigators.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Support: Arc aims to provide first-class support—operationally, financially and scientifically—that will enable scientists to pursue long-term high risk, high reward research that can meaningfully advance progress in disease cures, including neurodegeneration, cancer, and immune dysfunction.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Culture: We believe that culture matters enormously in science and that excellence is difficult to sustain. We aim to create a culture that is focused on scientific curiosity, a deep commitment to truth, broad ambition, and selfless collaboration.&amp;nbsp;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;Arc scaled to nearly 100 people in its first year. With $650M+ in committed funding and a state of the art new lab facility in Palo Alto, Arc will continue to grow quickly to several hundred in the coming years.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;About the position&amp;nbsp;&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;We are seeking an exceptional scientific leader and researcher to build and manage the Bioinformatics Center at the Arc Institute. The Center will be internally funded and staffed by research scientists under industry-competitive pay scales, with the overall mission of deploying and advancing multi-omic and functional genomics technologies to understand complex diseases.&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;About you&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;You love data and biology.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;You love creating new innovative computational approaches and algorithms to analyze biological data to generate novel biological insight. You understand the gaps in this field and can develop novel solutions and tools to address them.&lt;/li&gt;
&lt;li&gt;You love creating computational technologies and platforms that are scalable and useful in many different areas of biology.&lt;/li&gt;
&lt;li&gt;You are a collaborator. You’re an expert in your domain and you greatly enjoy working successfully with scientists from other teams, labs and scientific domains. You believe that working on projects with scientists from different backgrounds can lead to the most exciting and successful research.&lt;/li&gt;
&lt;li&gt;You can communicate equally well with both wet lab biologists and software engineers, and you enjoy working with both.&lt;/li&gt;
&lt;li&gt;You love to learn. As much as you love working with other people, you also love learning from them, learning new skills, and staying up-to-date on the latest in the field.&lt;/li&gt;
&lt;li&gt;You are a leader and a mentor. You find joy in hiring, mentoring, and developing the people you lead both scientifically and professionally, and you enjoy teaching others.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;In this position you will&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Build and manage Arc’s fully funded Bioinformatics Center of 3-5 FTEs.&lt;/li&gt;
&lt;li&gt;Actively mentor and provide guidance to research staff and develop them professionally and scientifically.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Partner with Arc’s Core Investigators and Technology Centers, Platforms, and Core Facilities to advance research across the institute and create a culture of collaboration and excellence.&lt;/li&gt;
&lt;li&gt;Develop and refine cutting edge data analysis approaches across Arc’s key research areas, including functional genomics, transcriptomics, epigenomics, and proteomics.&lt;/li&gt;
&lt;li&gt;Develop a strategy to curate and analyze existing large scale publicly available data across these areas to inform experimental research across the Institute.&lt;/li&gt;
&lt;li&gt;Develop a strategy to integrate multiple data types to elucidate functional connectivity between genes, transcripts, and proteins, with the goal of developing better standard models of gene expression and function.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Be a key participant in a collaborative, Institute-wide initiative on functional genomics focused on mechanistic understanding of late-onset Alzheimer’s disease.&lt;/li&gt;
&lt;li&gt;Develop a user-friendly and comprehensive data management system for research across the institute in collaboration with the Multi-Omics and Computation Technology Centers and the Institute’s IT function.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Serve as a subject matter expert across Arc in key areas of focus for the Center&lt;/li&gt;
&lt;li&gt;In collaboration with the Genome Engineering Technology Center, develop and refine approaches for genomic mining, discovery, and prioritization of new effectors and systems for bioengineering applications.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Engage in and manage internal and external research collaborations.&lt;/li&gt;
&lt;li&gt;Attend and present at team meetings to share results, plan projects and experiments, and ensure that projects support team goals.&amp;nbsp;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Job Requirements&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;PhD, MD, or MD/PhD in a relevant field and 5+ years of relevant experience in industry and academic settings.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;For director-level, 10+ years of relevant experience and 4+ years of experience managing, leading, and growing scientific teams.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;For associate director-level, previous managerial experience is preferred.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Extensive experience with genomics, transcriptomics, epigenomics, and single cell sequencing data analysis.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Experience developing innovative computational algorithms to address biological questions.&lt;/li&gt;
&lt;li&gt;Outstanding written and verbal communication skills are required for research presentations, SOP development, and publications.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;The successful candidate will be an ambitious self-starter, be motivated to apply his/her skills to diverse projects, and enjoy working in a fast-paced team environment&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Roles with discretionary bonuses:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;The base salary range for this position is $194,500 to $267,500. These amounts reflect the range of base salary that the Institute reasonably would expect to pay a new hire or internal candidate for this position. The actual base compensation paid to any individual for this position may vary depending on factors such as experience, market conditions, education/training, skill level, &lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;and whether the compensation is internally equitable,&lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; and does not include bonuses, commissions, differential pay, other forms of compensation, or benefits. This position is also eligible to receive an annual discretionary bonus, with the amount dependent on individual and institute performance factors.&lt;/span&gt;&lt;/p&gt;

Headquarters - 3181 Porter Drive, Palo Alto, CA

&lt;p&gt;&lt;strong&gt;About Arc Institute&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;The Arc Institute is a new scientific institution that conducts curiosity-driven basic science and technology development to understand and treat complex human diseases. Headquartered in Palo Alto, California, Arc is an independent research organization founded on the belief that many important research programs will be enabled by new institutional models. Arc operates in partnership with Stanford University, UCSF, and UC Berkeley.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;While the prevailing university research model has yielded many tremendous successes, we believe in the importance of institutional experimentation as a way to make progress. These include:&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Funding: &lt;/strong&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Arc will fully fund Core Investigator’s (PI’s) research groups, liberating scientists from the typical constraints of project-based external grants.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Technology:&lt;/strong&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; Biomedical research has become increasingly dependent on complex tooling. Arc Technology Centers develop, optimize and deploy rapidly advancing experimental and computational technologies in collaboration with Core Investigators.&amp;nbsp;&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Support:&lt;/strong&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; Arc aims to provide first-class support—operationally, financially and scientifically—that will enable scientists to pursue long-term high risk, high reward research that can meaningfully advance progress in disease cures, including neurodegeneration, cancer, and immune dysfunction.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Culture:&lt;/strong&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; We believe that culture matters enormously in science and that excellence is difficult to sustain. We aim to create a culture that is focused on scientific curiosity, a deep commitment to truth, broad ambition, and selfless collaboration.&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Arc scaled to nearly 100 people in its first year. With $650M+ in committed funding and a state of the art new lab facility in Palo Alto, Arc will continue to grow quickly to several hundred in the coming years.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;About the position&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;We are looking for an Associate Director to join our Genome Engineering Technology Center and lead the development of cutting-edge functional genomics approaches focused on the high-throughput interrogation of mammalian genomes, transcriptomes and epigenomes with rich multi-omic readouts. You will work closely with scientists and research associates in Arc’s Technology Centers and Core Investigator labs with a mission to develop technology to understand and treat complex genetic disease. The ideal candidate will have a passion for technology development and a proven track record in developing high-throughput CRISPR screens in mammalian cell culture or animal models.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;This is an excellent opportunity for a highly motivated and curious scientist and project leader interested in the intersection of basic research and biotech product development. Title and compensation will be competitive with industry jobs relative to experience level and background.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;About You&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;You are a leader and an expert in functional genomics. You think about gaps in the functional genomics space and know the kind of hiring that needs to be done to fill those gaps.&amp;nbsp;&amp;nbsp;&lt;/li&gt;
&lt;li&gt;You are innovative. You think deeply about what cutting edge tools you and your team can develop to better understand human health.&lt;/li&gt;
&lt;li&gt;You are a collaborator. You’re an expert in your domain and you greatly enjoy working successfully with scientists from other teams, labs and scientific domains. You believe that working on projects with scientists from different backgrounds can lead to the most exciting and successful research.&lt;/li&gt;
&lt;li&gt;You build tools. As much as you love answering specific scientific questions, you also love creating technology and platforms that are scalable and useful in many different scientific application areas.&lt;/li&gt;
&lt;li&gt;You are a problem solver. You are someone that can troubleshoot problems either for yourself or for the team.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;You are curious. As much as you love answering questions, you also love creating/asking new ones.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;In this position you will&amp;nbsp;&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Aid in building and managing the functional genomics team through recruiting, mentoring and training a team of scientists and research associates&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Work with other scientific leaders at Arc to develop a technology roadmap for functional genomics innovation&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Work closely with core investigators and internal and external collaborators to gather needs and define project scopes and priorities&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Provide technical assistance and help troubleshoot functional genomics and pooled screens for technology center projects and across the organization&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Drive functional genomics technology development projects from concept through development and technology transfer&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Manage multiple projects, with responsibility for planning, tracking, and driving timely execution of research activities&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Report progress and present data in internal and external meetings&amp;nbsp;&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Job Requirements&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;PhD in molecular biology, bioengineering, genomics, cell biology or similar fields&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;8+ years of post-PhD experience in academia or the biotechnology industry&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;3+ years of previous managerial experience leading and growing scientific teams of 3+&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Demonstrated ability to develop novel functional genomics screens with a record of academic publications or intellectual property&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Deep understanding of CRISPR editing systems and their application to pooled screens&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Hands-on experience with culturing various mammalian cell types including cancer cell lines, stem cells and primary cells&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Experience working with and developing functional genomics screens in animal models is desirable but not required&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Ability to design editing reagents for high-throughput pooled screens and analyze large, complex data sets using tools such as Python and R&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Ability and desire to work in a fast-paced environment and be a team player&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;Roles with discretionary bonuses:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;The base salary range for this position is $147,000 to $171,000. These amounts reflect the range of base salary that the Institute reasonably would expect to pay a new hire or internal candidate for this position. The actual base compensation paid to any individual for this position may vary depending on factors such as experience, market conditions, education/training, skill level, &lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;and whether the compensation is internally equitable,&lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; and does not include bonuses, commissions, differential pay, other forms of compensation, or benefits. This position is also eligible to receive an annual discretionary bonus, with the amount dependent on individual and institute performance factors.&lt;/span&gt;&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;About Arc Institute&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;The Arc Institute is a new scientific institution that conducts curiosity-driven basic science and technology development to understand and treat complex human diseases. Headquartered in Palo Alto, California, Arc is an independent research organization founded on the belief that many important research programs will be enabled by new institutional models. Arc operates in partnership with Stanford University, UCSF, and UC Berkeley.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;While the prevailing university research model has yielded many tremendous successes, we believe in the importance of institutional experimentation as a way to make progress. These include:&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Funding: &lt;/strong&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Arc will fully fund Core Investigator’s (PI’s) research groups, liberating scientists from the typical constraints of project-based external grants.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Technology:&lt;/strong&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; Biomedical research has become increasingly dependent on complex tooling. Arc Technology Centers develop, optimize and deploy rapidly advancing experimental and computational technologies in collaboration with Core Investigators.&amp;nbsp;&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Support:&lt;/strong&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; Arc aims to provide first-class support—operationally, financially and scientifically—that will enable scientists to pursue long-term high risk, high reward research that can meaningfully advance progress in disease cures, including neurodegeneration, cancer, and immune dysfunction.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Culture:&lt;/strong&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; We believe that culture matters enormously in science and that excellence is difficult to sustain. We aim to create a culture that is focused on scientific curiosity, a deep commitment to truth, broad ambition, and selfless collaboration.&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Arc scaled to nearly 100 people in its first year. With $650M+ in committed funding and a state of the art new lab facility in Palo Alto, Arc will continue to grow quickly to several hundred in the coming years.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;About the position&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;We are seeking an exceptional scientific leader and researcher to build and manage the Cellular Models Center, one of the foundational Technology Centers at the Arc Research Institute. The Center will be internally funded and staffed by professional research scientists, with the overall mission of developing cellular models of human disease. One of the initial goals will be to create 2D and 3D human cellular models to model Alzheimer’s disease and other neurodegenerative disorders using stem cell-derived neurons, astrocytes, and microglia. The Center will also develop scalable strategies for creating complex, multi-cell type cultures and organoids that are compatible with cutting edge genetic screening approaches. Over time, the Center will expand to develop other models for immune-related conditions in addition to CNS disorders. Collaborations with Core Laboratories and other Centers at the institute will enable high-throughput interrogation of these models for target identification, investigation of human genetic variants using gene editing and functional genomics, and development of rational therapeutic strategies.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;About you&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;You are a scientific leader and an expert in neural and other cellular models. You think about gaps in the cellular models space and know the kind of experts you need to hire to address these gaps.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;You love building cellular models, research and innovation. You bridge the gap between creating the innovative tools to make reproducible, innovative and scalable cellular models to answer biological questions with the ability to generate meaningful insight into biological disease.You think about cellular models from both developmental biology and pathophysiology perspectives.&lt;/li&gt;
&lt;li&gt;You are a collaborator. You’re an expert in your domain and you greatly enjoy working successfully with scientists from other teams, labs and scientific domains. You believe that working on projects with scientists from different backgrounds can lead to the most exciting and successful research.&lt;/li&gt;
&lt;li&gt;You love to learn. As much as you love working with other people, you also love learning from them, learning new skills, and staying up-to-date on the latest in the field.&lt;/li&gt;
&lt;li&gt;You are a mentor. Being a great scientific leader doesn’t stop at hiring your team. You love mentoring and developing people both professionally and scientifically – both in your team as well as other scientific teams at Arc.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;In this position, you will&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Build and manage a fully funded Cellular Models Technology Center of ~10 FTEs&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Actively mentor and provide guidance to research staff and develop them professionally and scientifically&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Partner with Principal Investigators and other Technology Centers to advance research across the institute and create a culture of collaboration and excellence&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Develop state of the art protocols, resources, and processes for advanced cellular modeling that is actively deployed at the institute and distributed to the broader scientific community&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Serve as a subject matter expert in key areas of focus, such as developmental biology, stem cell biology, and neurobiology&amp;nbsp;&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Engage in and manage internal and external research collaborations&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Present research findings at institute meetings and external scientific conferences&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Job Requirements&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;PhD, DVM/PhD, MD, or MD/PhD in a relevant field and 10 – 15 years of relevant experience in industry and academic settings&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Previous managerial experience leading and growing scientific teams&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Advanced experience with human stem cell culture, iPSC derivation, and optimization of reproducible stem cell differentiation approaches&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Experience with 3D model approaches (e.g. organoid or assembled spheroids)&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Experience with modeling of diverse brain cell types (excitatory/inhibitory neurons, astrocytes and microglia)&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Experience with functional and genomic analysis of cellular model (e.g. bulk or single cell transcriptomic characterization, live cell imaging, or electrophysiology)&amp;nbsp;&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Outstanding written and verbal communication skills is required for research presentations, SOP development, and publications&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;The successful candidate will be an ambitious self-starter, be motivated to apply his/her skills to diverse projects and enjoy working in a fast-paced team environment.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Familiarity with computational requirements of model characterization, and ability to interface with bioinformaticians in the Computational Biology Center.&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Roles with discretionary bonuses:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;The base salary range for this position is $162,000 to $262,500. These amounts reflect the range of base salary that the Institute reasonably would expect to pay a new hire or internal candidate for this position. The actual base compensation paid to any individual for this position may vary depending on factors such as experience, market conditions, education/training, skill level, &lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;and whether the compensation is internally equitable,&lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; and does not include bonuses, commissions, differential pay, other forms of compensation, or benefits. This position is also eligible to receive an annual discretionary bonus, with the amount dependent on individual and institute performance factors.&lt;/span&gt;&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;About Arc Institute&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;The Arc Institute is a new scientific institution that conducts curiosity-driven basic science and technology development to understand and treat complex human diseases. Headquartered in Palo Alto, California, Arc is an independent research organization founded on the belief that many important research programs will be enabled by new institutional models. Arc operates in partnership with Stanford University, UCSF, and UC Berkeley.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;While the prevailing university research model has yielded many tremendous successes, we believe in the importance of institutional experimentation as a way to make progress. These include:&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Funding: &lt;/strong&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Arc will fully fund Core Investigator’s (PI’s) research groups, liberating scientists from the typical constraints of project-based external grants.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Technology:&lt;/strong&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; Biomedical research has become increasingly dependent on complex tooling. Arc Technology Centers develop, optimize and deploy rapidly advancing experimental and computational technologies in collaboration with Core Investigators.&amp;nbsp;&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Support:&lt;/strong&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; Arc aims to provide first-class support—operationally, financially and scientifically—that will enable scientists to pursue long-term high risk, high reward research that can meaningfully advance progress in disease cures, including neurodegeneration, cancer, and immune dysfunction.&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;Arc scaled to nearly 100 people in its first year. With $650M+ in committed funding and a state of the art new lab facility in Palo Alto, Arc will continue to grow quickly to several hundred in the coming years.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;About the position&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;The Arc team is expanding quickly and we are looking for an experienced IT leader to oversee the Institute’s IT systems and projects. The IT Manager will manage all information technology systems at Arc. In addition, the IT Manager will design and implement Arc’s future IT roadmap to best support Arc’s ambitious research goals.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;About you&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;&lt;strong&gt;You connect with people&lt;/strong&gt;. You know that successful systems are more about the user than the tool. You enjoy building relationships and credibility with your colleagues.&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;You enjoy solving problems.&lt;/strong&gt; Any new project is an interesting puzzle. So is a tricky troubleshooting issue. You get satisfaction from helping someone get to resolution.&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;You’re curious.&lt;/strong&gt; You like to keep track of the latest developments in your field, and to learn about the substance behind your employer’s mission.&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;You’re organized.&lt;/strong&gt; You enjoy bringing order to chaos and helping others wrangle complexity and ambiguity.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;In this position you will&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Ensure an exceptional level of IT system performance and support to users in scientific labs and our operations team.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Set a long term strategy and roadmap for IT at Arc; set and execute on quarterly goals alongside other functions&lt;/li&gt;
&lt;li&gt;Define and manage technical IT projects through the full lifecycle - from user needs to planning to execution, through to deployment and training.&lt;/li&gt;
&lt;li&gt;Implement and monitor essential IT operations, including servers and cloud computing, operating systems, security tools, applications, email systems, laptops, desktops, software, and hardware.&lt;/li&gt;
&lt;li&gt;Manage IT vendors providing front-end helpdesk support to Arc, eventually managing an in house team.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Collaborate with other technical support teams including Lab Operations, Facilities, Infrastructure, and others to ensure alignment and shared execution on meeting Arc’s ongoing needs.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Develop user communications, user guides, and training programs to increase end user computer literacy and self-sufficiency.&lt;/li&gt;
&lt;li&gt;Develop business continuity procedures, and maintain data backups.&lt;/li&gt;
&lt;li&gt;Develop and manage an overall IT budget that effectively supports Arc’s IT efforts.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Requirements&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Bachelor’s degree in Information Systems, Technology, or related field, or equivalent.&lt;/li&gt;
&lt;li&gt;7+ years of experience in IT, 3+ years of supervisory experience managing IT resources.&lt;/li&gt;
&lt;li&gt;Exceptional written and verbal communications skills and ability to take in and synthesize complex nuanced information from many different perspectives.&lt;/li&gt;
&lt;li&gt;Experience with Windows and MacOS environments, G Suite, Microsoft 365.&lt;/li&gt;
&lt;li&gt;Demonstrated knowledge of technical system management, information security management, computer and network hardware, and desktop and cloud software solutions.&lt;/li&gt;
&lt;li&gt;Strong analytical and problem-solving skills for troubleshooting and resolving complex systems issues.&lt;/li&gt;
&lt;li&gt;High level of tolerance and flexibility to address complex cross-functional issues and to reach compromises with key stakeholders&lt;/li&gt;
&lt;li&gt;Proven track record for working independently in a fast-paced startup environment.&lt;/li&gt;
&lt;li&gt;​​Good understanding of lab environments and scientific technology needs is a plus.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;The base salary range for this position is $159,500-$181,500. These amounts reflect the range of base salary that the Institute&amp;nbsp;&lt;span style=&quot;color: rgb(0, 0, 0);&quot;&gt;reasonably would expect to pay a new hire or internal candidate for this position. The actual&amp;nbsp;base&amp;nbsp;compensation paid to any individual for this position may vary depending on factors such as experience, internal equity, market conditions, education/training, and skill level, and does not include bonuses, commissions, differential pay, other forms of compensation, or benefits.&amp;nbsp;This position is also eligible to receive an annual discretionary bonus, with the amount dependent on individual and institute performance factors.&lt;/span&gt;&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;About Arc Institute&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;The Arc Institute is a new scientific institution that conducts curiosity-driven basic science and technology development to understand and treat complex human diseases. Headquartered in Palo Alto, California, Arc is an independent research organization founded on the belief that many important research programs will be enabled by new institutional models. Arc operates in partnership with Stanford University, UCSF, and UC Berkeley.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;While the prevailing university research model has yielded many tremendous successes, we believe in the importance of institutional experimentation as a way to make progress. These include:&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Funding: &lt;/strong&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Arc will fully fund Core Investigator’s (PI’s) research groups, liberating scientists from the typical constraints of project-based external grants.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Technology:&lt;/strong&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; Biomedical research has become increasingly dependent on complex tooling. Arc Technology Centers develop, optimize and deploy rapidly advancing experimental and computational technologies in collaboration with Core Investigators.&amp;nbsp;&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Support:&lt;/strong&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; Arc aims to provide first-class support—operationally, financially and scientifically—that will enable scientists to pursue long-term high risk, high reward research that can meaningfully advance progress in disease cures, including neurodegeneration, cancer, and immune dysfunction.&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;Arc scaled to nearly 100 people in its first year. With $650M+ in committed funding and a state of the art new lab facility in Palo Alto, Arc will continue to grow quickly to several hundred in the coming years.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;About the position&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;As Arc’s Infrastructure Engineering Manager, you will build, deploy, and maintain computing systems that enable cutting edge scientific research. You’ll collaborate closely with our Core Investigators and Tech Centers, apply your expertise, and manage key vendors, consultants, and cloud providers to ensure that Arc has world class infrastructure. This is an opportunity to build the infrastructure technology stack from the ground up for sophisticated users. This is an individual contributor role with potential to grow and manage a small team over time. Some examples of the kinds of work you will own and build:&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;
&lt;p&gt;Large scale data processing workflows that synchronize across on-prem and cloud environments&amp;nbsp;&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Scheduled and on-demand GPU-accelerated workloads for ML training and validation&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Data ingestion and pipelines from scientific instruments to storage and analysis&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Data lake/warehousing/cold storage&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Analytics tooling and reporting&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;User access and management&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Comprehensive metrics, monitoring, and alerting to ensure our infrastructure is highly available and scalable&lt;/p&gt;
&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;About you&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;
&lt;p&gt;You love to build. Whether it’s new infrastructure from scratch or adding capabilities to a large-scale operation, you enjoy the work to define and execute on a new project instead of just maintaining it.&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;You are a collaborator. You like building relationships as much as writing code. You’ve experienced the super power of great teamwork and seek out opportunities to create with colleagues.&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;You care about more than the tech stack. You know the tools and frameworks, but you like to understand the why and the who, the purpose behind the system, and the people who are going to use it.&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;You think strategically. You believe that high quality results come from a clear plan. You like looking weeks, months, or years ahead to make sure you’re building the right thing for the long term.&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;You are inspired by science. Whether you have worked in biotech or barely know what CRISPR is, you see the transformational potential of computational biology, and want to contribute to advancing the field with your expertise.&lt;/p&gt;
&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;In this position you will&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;
&lt;p&gt;Develop a comprehensive strategy, roadmap, and budget for computational infrastructure at Arc that meets current and future needs&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Learn or build on an understanding of the research, data, and computational use cases in Arc’s focus areas&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Collaborate closely with Arc’s science and operations teams to enable world class research and results&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Build and deploy on-prem, cloud, and orchestration resources that efficiently and effectively support our research paths&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Ensure the scalability, reliability, and security of our infrastructure and applications&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Collaborate with other Operations teams to set goals, build teams, problem solve, and develop a unique culture&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Manage vendors and consultants who contribute to Arc’s infrastructure needs&lt;/p&gt;
&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Requirements&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;
&lt;p&gt;A Bachelor&#39;s degree in computer science or related fields; master’s degree preferred&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;8+ years experience building infrastructure for machine learning and/or other intensive computing applications; some exposure to life sciences preferred&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Familiarity with major cloud provider capabilities such as GCP and AWS&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Experience with GPU compute frameworks such as CUDA, job schedulers such as LSF/Slurm, and other infrastructure relevant technologies such as Python and Linux&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Exposure to key hardware components such as storage arrays, databases, on-prem CPU and CPU based compute clusters, gigabit ethernet, and other real world infrastructure&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Previous experience managing on-prem and cloud infrastructure at large scale&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Exceptionally strong communication and information synthesis skills&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Experience working in a fast paced startup environment with high levels of collaboration and many inputs&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Skilled influencer with ability to form strong relationships across all levels and functions at Arc&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Excellent problem solving and analytical skills with the ability to design solutions in an ambiguous environment&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Bias for action with ability to lead both tactically and strategically&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Demonstrated ability to build programs, processes, and metrics in a scaling organization&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;A little humor&lt;/p&gt;
&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;The base salary range for this position is $168,500 - $211,500. These amounts reflect the range of base salary that the Institute&amp;nbsp;&lt;span style=&quot;color: rgb(0, 0, 0);&quot;&gt;reasonably would expect to pay a new hire or internal candidate for this position. The actual&amp;nbsp;base&amp;nbsp;compensation paid to any individual for this position may vary depending on factors such as experience, internal equity, market conditions, education/training, and skill level, and does not include bonuses, commissions, differential pay, other forms of compensation, or benefits.&amp;nbsp;This position is also eligible to receive an annual discretionary bonus, with the amount dependent on individual and institute performance factors.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;About Arc Institute&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;The Arc Institute is a new scientific institution that conducts curiosity-driven basic science and technology development to understand and treat complex human diseases. Headquartered in Palo Alto, California, Arc is an independent research organization founded on the belief that many important research programs will be enabled by new institutional models. Arc operates in partnership with Stanford University, UCSF, and UC Berkeley.&lt;/p&gt;
&lt;p&gt;While the prevailing university research model has yielded many tremendous successes, we believe in the importance of institutional experimentation as a way to make progress. These include:&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;&lt;strong&gt;Funding:&amp;nbsp;&lt;/strong&gt;Arc will fully fund Core Investigator’s (PI’s) research groups, liberating scientists from the typical constraints of project-based external grants.&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Technology:&lt;/strong&gt;&amp;nbsp;Biomedical research has become increasingly dependent on complex tooling. Arc Technology Centers develop, optimize and deploy rapidly advancing experimental and computational technologies in collaboration with Core Investigators.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Support:&lt;/strong&gt;&amp;nbsp;Arc aims to provide first-class support—operationally, financially and scientifically—that will enable scientists to pursue long-term high risk, high reward research that can meaningfully advance progress in disease cures, including neurodegeneration, cancer, and immune dysfunction.&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Culture:&lt;/strong&gt;&amp;nbsp;We believe that culture matters enormously in science and that excellence is difficult to sustain. We aim to create a culture that is focused on scientific curiosity, a deep commitment to truth, broad ambition, and selfless collaboration.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;Arc scaled to nearly 100 people in its first year. With $650M+ in committed funding and a state of the art new lab facility in Palo Alto, Arc will continue to grow quickly to several hundred in the coming years.&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;About the position:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Arc is searching for an experienced Lab Operations Manager who is passionate about operational excellence, collaboration and high communication.&amp;nbsp;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Reporting to the Head of Laboratory Operations, the Laboratory Operations Manager will be&amp;nbsp; responsible for solving day-to-day logistical challenges associated with the startup of a new&amp;nbsp; research institution. &lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;By actively identifying and facilitating operational excellence opportunities, you will provide first-class support to Arc scientists working with other members of Arc’s Research Operations team. Additionally, you will facilitate lab transitions for new faculty hires to the Arc labs in Palo Alto, CA and act as a liaison between the research and operational teams.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;About you:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;You love to build from the ground up. You enjoy the work to create new structures and processes instead of just maintaining them.&lt;/li&gt;
&lt;li&gt;You are a collaborator and influencer. You value building relationships to get the information and insights you need for your job and work directly with the labs.&amp;nbsp; You’ve experienced the superpower of great teamwork and are comfortable influencing upward and across an organization.&lt;/li&gt;
&lt;li&gt;You care about more than the lab operations. You like to understand the why and the who, the purpose behind the system, and the people who are going to use it.&lt;/li&gt;
&lt;li&gt;You think strategically. You believe that high quality results come from a clear plan. You like looking weeks, months, or years ahead to make sure you’re building the right thing for the long term.&lt;/li&gt;
&lt;li&gt;You are detail oriented. The small things matter, you would spot safety issues and a clean lab is a thing of beauty in your eyes.You are inspired by science. You see the transformational potential of biological research, and want to contribute to advancing the field with your expertise.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;In this position you will:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Manage day-to-day operations of a mixed lab and office space across 100,000 sq ft. including molecular biology and tissue culture laboratories.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Oversee smooth and efficient use of Arc lab space, including optimization of research workflows and shared space usage.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;In strong collaboration with the labs and end-users development, maintain and upkeep systems and applications, including monitoring systems, ticketing systems, ordering/inventory systems, and scheduling systems.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Work collaboratively with other members of the Lab Operations team, who oversee procurement (shipping/receiving), stocking, and lab services (autoclave/glasswash), etc.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Review and document scientific workflows.&amp;nbsp;&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Develop and update equipment SOPs in collaboration with the super- users, labs and tech centers.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Assist with instrument training, scheduling, and maintenance.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Participating in onboarding lab members, including the evaluation and intake of incoming labs and their needs to ensure that things are set up from equipment to supplies, EH&amp;amp;S and instrument training, and more.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Assist lab owners with coordinating equipment moves and installations, ensuring site of installation met criteria for system operation, functional support and space.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Develop robust supply management workflows&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;table&gt;
&lt;tbody&gt;
&lt;tr&gt;
&lt;td&gt;
&lt;p&gt;&lt;strong&gt;Requirements:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;7+ years of operational support in a wet and dry laboratory scientific setting.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;5+ years of experience in managing multiple projects.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Strong understanding of workflows in shared life science laboratories.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Excellent cross-functional communication skills including an ability to partner and negotiate with labs, PI’s and senior management&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Highly organized, with a drive to actively improve process and workflows.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Goal oriented with passion for independently working through defined goals and metrics.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Highly collaborative with great enthusiasm for working across cross-functional teams.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Able to calmly and positively navigate shifting priorities and rapid change.&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;The base salary range for this position is $84,000 to $132,000. These amounts reflect the range of base salary that the Institute reasonably would expect to pay a new hire or internal candidate for this position. The actual base compensation paid to any individual for this position may vary depending on factors such as experience, market conditions, education/training, skill level, and whether the compensation is internally equitable, and does not include bonuses, commissions, differential pay, other forms of compensation, or benefits. This position is also eligible to receive an annual discretionary bonus, with the amount dependent on individual and institute performance factors.&lt;/span&gt;&lt;/p&gt;
&lt;/td&gt;
&lt;/tr&gt;
&lt;/tbody&gt;
&lt;/table&gt;

&lt;p&gt;&lt;strong&gt;About Arc Institute&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;The Arc Institute is a new scientific institution that conducts curiosity-driven basic science and technology development to understand and treat complex human diseases. Headquartered in Palo Alto, California, Arc is an independent research organization founded on the belief that many important research programs will be enabled by new institutional models. Arc operates in partnership with Stanford University, UCSF, and UC Berkeley.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;While the prevailing university research model has yielded many tremendous successes, we believe in the importance of institutional experimentation as a way to make progress. These include:&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Funding: &lt;/strong&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Arc will fully fund Core Investigator’s (PI’s) research groups, liberating scientists from the typical constraints of project-based external grants.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Technology:&lt;/strong&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; Biomedical research has become increasingly dependent on complex tooling. Arc Technology Centers develop, optimize and deploy rapidly advancing experimental and computational technologies in collaboration with Core Investigators.&amp;nbsp;&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Support:&lt;/strong&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; Arc aims to provide first-class support—operationally, financially and scientifically—that will enable scientists to pursue long-term high risk, high reward research that can meaningfully advance progress in disease cures, including neurodegeneration, cancer, and immune dysfunction.&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;Arc scaled to nearly 100 people in its first year. With $650M+ in committed funding and a state of the art new lab facility in Palo Alto, Arc will continue to grow quickly to several hundred in the coming years.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;About the position&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;This role sits on the People Operations team and is the face of the team for many of the employees at Arc. From onboarding to programs and partnering with the people across the organization, you’ll have the opportunity to work as part of a high performing team and learn the full HR stack. This position provides practical experience and is a training ground for many different types of roles in the people domain.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;About you&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;You value providing great service experiences and strive to understand the needs of the people you’re supporting. You are highly detail oriented and eager to build new skills related to data and project management. You enjoy working closely with colleagues and look for the best in others.&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;In this position you will&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Be the first point of contact for employees and managers related to benefits, payroll, systems, programs and more. You will also help to coordinate responses to questions that require input from others on the team.&lt;/li&gt;
&lt;li&gt;Be a welcoming front door to Arc and manage new hire paperwork throughout the onboarding process.&lt;/li&gt;
&lt;li&gt;Maintain accurate employee records in our HRIS and related HR systems, including documenting changes in status and document management.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Work with our Payroll and Benefits Partners to manage employee benefits enrollment and changes in status.&lt;/li&gt;
&lt;li&gt;Support our program leaders in running our people programs by providing scheduling support, material creation, record keeping, project management and administrative support.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Manage the day to administration of our COVID policy, including notifications and communication with employees.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Work with our People Operations team to audit data and ensure our records are accurate.&lt;/li&gt;
&lt;li&gt;Manage swag inventory.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Requirements&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;1-3 years of experience supporting people operations and/or human resources.&lt;/li&gt;
&lt;li&gt;Detail oriented, you’re able to consistently complete work with a high degree of accuracy.&lt;/li&gt;
&lt;li&gt;Strong communicator, you’re able to synthesize relevant information and effectively communicate in both written and verbal formats.&lt;/li&gt;
&lt;li&gt;Comfortable with new technology, you’re able to effectively use modern office tools and quickly learn and adapt to new technology systems.&lt;/li&gt;
&lt;li&gt;Service minded, you’re oriented towards creating a positive experience for the people you’re working with and supporting.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Well organized, you have a system for staying organized and are always looking for ways to improve.&lt;/li&gt;
&lt;li&gt;Adaptive, you are open to change and adapting the way you work based on evolving needs.&lt;/li&gt;
&lt;li&gt;Focused on growth, you’re eager to learn from experience and take an active role in your development.&amp;nbsp;&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Willingness to work onsite in Palo Alto.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;The base salary range for this position is $38.40/hr to $41.53/hr. These amounts reflect the range of base salary that the Institute reasonably would expect to pay a new hire or internal candidate for this position. The actual base compensation paid to any individual for this position may vary depending on factors such as experience, market conditions, education/training, skill level, and whether the compensation is internally equitable, and does not include bonuses, commissions, differential pay, other forms of compensation, or benefits. This position is also eligible to receive an annual discretionary bonus, with the amount dependent on individual and institute performance factors.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;About Arc Institute&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;The Arc Institute is a new scientific institution that conducts curiosity-driven basic science and technology development to understand and treat complex human diseases. Headquartered in Palo Alto, California, Arc is an independent research organization founded on the belief that many important research programs will be enabled by new institutional models. Arc operates in partnership with Stanford University, UCSF, and UC Berkeley.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;While the prevailing university research model has yielded many tremendous successes, we believe in the importance of institutional experimentation as a way to make progress. These include:&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Funding: &lt;/strong&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Arc will fully fund Core Investigator’s (PI’s) research groups, liberating scientists from the typical constraints of project-based external grants.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Technology:&lt;/strong&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; Biomedical research has become increasingly dependent on complex tooling. Arc Technology Centers develop, optimize and deploy rapidly advancing experimental and computational technologies in collaboration with Core Investigators.&amp;nbsp;&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Support:&lt;/strong&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; Arc aims to provide first-class support—operationally, financially and scientifically—that will enable scientists to pursue long-term high risk, high reward research that can meaningfully advance progress in disease cures, including neurodegeneration, cancer, and immune dysfunction.&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;Arc scaled to nearly 100 people in its first year. With $650M+ in committed funding and a state of the art new lab facility in Palo Alto, Arc will continue to grow quickly to several hundred in the coming years.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;About the position:&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Arc Institute is seeking applications for a Scientific Advisor to our Recruiting team to help us achieve our hiring goals. Arc is in a rapid growth phase, aiming to build five Technology Centers, recruit new Core and Affiliate faculty members, and hire additional researchers in Core Investigators’ labs. Proactive outreach to connect with top academic labs and biotech companies with relevant expertise will be crucial to recruiting the best talent to Arc for years to come. As an integral member of our team, the Scientific Recruiting Advisor will bring broad scientific expertise, top-notch communication skills, decisive scientific scrutiny, and a team-focused approach to match candidates to roles and disseminate Arc’s unique model and vision.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;About you:&amp;nbsp;&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;You are passionate about science. You have built and continue to maintain broad scientific expertise. You enjoy talking about a wide variety of scientific research disciplines and are excited to learn about new scientific fields.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;You are curious and collaborative. You love learning and have a genuine interest in people, ideas and unfamiliar topics.&amp;nbsp; You enjoy research and asking questions to dig deep in a particular area. You like to tackle new challenges and solve complex puzzles with others. You appreciate the power of great teamwork in an optimistic environment. You take the time to be an active listener and are open to new or different ideas and viewpoints.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;You approach problem solving with creativity and resilience. You strive to find innovative solutions to problems. You aren’t afraid to try a new approach.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;You value relationship building and care about creating a positive experience for people interviewing at Arc. You enjoy making connections with new people. You approach your work and relationship building with clear communication, transparency, empathy and kindness.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;In this role you will:&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Collaborate with Arc Institute leadership and hiring managers to define, draft, and understand requirements for scientific positions at all levels.&lt;/li&gt;
&lt;li&gt;Create robust pipelines through active sourcing and develop outreach messaging for potential candidates for various scientific roles.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Interview and evaluate inbound and sourced candidates for various scientific roles.&lt;/li&gt;
&lt;li&gt;Use your networks and knowledge of the academic and biotech landscapes to proactively build relationships with top candidates that would complement Arc’s scientific needs and contribute to a culture of scientific curiosity, rigor, ambition, and collaboration.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;Partner with the recruiting team to build efficient and scalable recruiting processes.&lt;/li&gt;
&lt;li&gt;Proudly represent Arc’s mission and values through the hiring process.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Requirements:&amp;nbsp;&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;PhD in a relevant life science discipline&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;3+ years of post PhD experience&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Broad scientific literacy and ability to critically evaluate scientific research across disciplines including biochemistry, cell biology, neuroscience, cancer biology, immunology and genomics&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Familiarity with the academic landscape in the US and worldwide&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Familiarity with the biotech industry and a relevant professional network is a plus&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Experience working in cross-functional teams and communicating scientific concepts to non-scientist team members&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Exceptional written and verbal communication skills&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Experience interviewing job applicants and/or assessing scientific manuscripts or grants&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;The base salary range for this position is $89,000 to $145,000. &lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;These amounts reflect the range of base salary that the Institute reasonably would expect to pay a new hire or internal candidate for this position. The actual base compensation paid to any individual for this position may vary depending on factors such as experience, market conditions, education/training, skill level, &lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;and whether the compensation is internally equitable,&lt;/span&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; and does not include bonuses, commissions, differential pay, other forms of compensation, or benefits. This position is also eligible to receive an annual discretionary bonus, with the amount dependent on individual and institute performance factors.&lt;/span&gt;&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;About Arc Institute&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;The Arc Institute is a new scientific institution conducting curiosity-driven basic science and technology development to understand and treat complex human diseases. Headquartered in Palo Alto, California, Arc is an independent research organization founded on the belief that many important research programs will be enabled by new institutional models. Arc operates in partnership with Stanford University, UCSF, and UC Berkeley.&lt;/p&gt;
&lt;p&gt;While the prevailing university research model has yielded many tremendous successes, we believe in the importance of institutional experimentation as a way to make progress. These include:&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;&lt;strong&gt;Funding: &lt;/strong&gt;Arc will fully fund Core Investigators’ (PIs’) research groups, liberating scientists from the typical constraints of project-based external grants.&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Technology:&lt;/strong&gt; Biomedical research has become increasingly dependent on complex tooling. Arc Technology Centers develop, optimize and deploy rapidly advancing experimental and computational technologies in collaboration with Core Investigators.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Support:&lt;/strong&gt; Arc aims to provide first-class support—operationally, financially and scientifically—that will enable scientists to pursue long-term high risk, high reward research that can meaningfully advance progress in disease cures, including neurodegeneration, cancer, and immune dysfunction.&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Culture:&lt;/strong&gt; We believe that culture matters enormously in science and that excellence is difficult to sustain. We aim to create a culture that is focused on scientific curiosity, a deep commitment to truth, broad ambition, and selfless collaboration.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;Arc scaled to nearly 100 people in its first year. With $650M+ in committed funding and a state of the art new lab facility in Palo Alto, Arc will continue to grow quickly to several hundred in the coming years.&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;About the position&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;We are looking for a Scientist to join our Genome Engineering Technology Center and support the development of cutting-edge functional genomics approaches focused on the high-throughput interrogation of mammalian genomes, transcriptomes and epigenomes with rich multi-omic readouts. You will work closely with other Scientists and Research Associates in Arc’s Technology Centers and Core Investigator labs with a mission to develop technology to understand and treat complex genetic disease. The ideal candidate will have a passion for technology development and a proven track record in developing high-throughput CRISPR screens in mammalian cell culture or animal models.&lt;/p&gt;
&lt;p&gt;This is an excellent opportunity for a highly motivated and curious scientist interested in the intersection of basic research and biotech product development. Title and compensation will be competitive with industry jobs relative to experience level and background.&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;About you&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;You love science and the opportunities it creates. Functional Genomics is a new field filled with unanswered biological questions. You find excitement in the opportunity to address these questions with your functional genomics expertise.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;You are a collaborator. You’re an expert in your domain and you greatly enjoy working successfully with scientists from other teams, labs and scientific domains. You believe that working on projects with scientists from different backgrounds can lead to the most exciting and successful research.&lt;/li&gt;
&lt;li&gt;You build tools. As much as you love answering specific scientific questions, you also love creating technology and platforms that are scalable and useful in many different scientific application areas.&lt;/li&gt;
&lt;li&gt;You are an optimizer. In science, there’s always a race against the clock. You care deeply about making every step of the way as close to perfect as possible but also as quick and efficient as possible.&amp;nbsp;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;In this position you will&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Design and run pooled functional genomics screens to prototype new technology and generate key data sets for technology development&lt;/li&gt;
&lt;li&gt;Work closely with core academic labs on collaborative projects to execute pooled functional genomics screens and answer important scientific questions&lt;/li&gt;
&lt;li&gt;Provide technical input to the Genome Engineering Technology Center roadmap for functional genomics technology development&lt;/li&gt;
&lt;li&gt;Manage multiple projects, with responsibility for planning, tracking, and driving timely execution of research activities&lt;/li&gt;
&lt;li&gt;Report progress and present data in internal and external meetings&amp;nbsp;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Job Requirements&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;PhD in molecular biology, bioengineering, genomics, cell biology or similar fields&lt;/li&gt;
&lt;li&gt;Demonstrated ability to implement pooled functional genomics screens with a record of academic publications or intellectual property&lt;/li&gt;
&lt;li&gt;Deep understanding of CRISPR editing systems and their application to pooled screens including gRNA design&lt;/li&gt;
&lt;li&gt;Hands-on experience with culturing and transfecting mammalian cell lines&lt;/li&gt;
&lt;li&gt;Ability to interpret pooled CRISPR screening data to answer key scientific questions and drive next steps in method development&lt;/li&gt;
&lt;li&gt;Experience working with and developing functional genomics screens in animal models is desirable but not required&lt;/li&gt;
&lt;li&gt;Experience developing pipelines for analyzing large-scale pooled screening data (eg. NGS) is desirable but not required&lt;/li&gt;
&lt;li&gt;Ability and desire to work in a fast-paced environment and be a team player&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;The base salary range for this position is $112,500 to $148,500. These amounts reflect the range of base salary that the Institute reasonably would expect to pay a new hire or internal candidate for this position. The actual base compensation paid to any individual for this position may vary depending on factors such as experience, market conditions, education/training, skill level, and whether the compensation is internally equitable, and does not include bonuses, commissions, differential pay, other forms of compensation, or benefits. This position is also eligible to receive an annual discretionary bonus, with the amount dependent on individual and institute performance factors.&lt;/span&gt;&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;About Arc Institute&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;The Arc Institute is a new scientific institution that conducts curiosity-driven basic science and technology development to understand and treat complex human diseases. Headquartered in Palo Alto, California, Arc is an independent research organization founded on the belief that many important research programs will be enabled by new institutional models. Arc operates in partnership with Stanford University, UCSF, and UC Berkeley.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;While the prevailing university research model has yielded many tremendous successes, we believe in the importance of institutional experimentation as a way to make progress. These include:&lt;/span&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Funding: &lt;/strong&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Arc will fully fund Core Investigator’s (PI’s) research groups, liberating scientists from the typical constraints of project-based external grants.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Technology:&lt;/strong&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; Biomedical research has become increasingly dependent on complex tooling. Arc Technology Centers develop, optimize and deploy rapidly advancing experimental and computational technologies in collaboration with Core Investigators.&amp;nbsp;&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Support:&lt;/strong&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; Arc aims to provide first-class support—operationally, financially and scientifically—that will enable scientists to pursue long-term high risk, high reward research that can meaningfully advance progress in disease cures, including neurodegeneration, cancer, and immune dysfunction.&lt;/span&gt;&lt;/li&gt;
&lt;li style=&quot;font-weight: 400;&quot;&gt;&lt;strong&gt;Culture:&lt;/strong&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt; We believe that culture matters enormously in science and that excellence is difficult to sustain. We aim to create a culture that is focused on scientific curiosity, a deep commitment to truth, broad ambition, and selfless collaboration.&lt;/span&gt;&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;Arc scaled to nearly 100 people in its first year. With $650M+ in committed funding and a state of the art new lab facility in Palo Alto, Arc will continue to grow quickly to several hundred in the coming years.&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;About the position&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;The Hsu and Konermann Labs at the Arc Institute are seeking applications for a Scientist or Senior Scientist position to be based at the Arc Institute in Palo Alto, CA, working in the areas of Molecular Technology Development, Genome Engineering, and Synthetic Biology. Our groups draw from a palette of technologies including DNA and RNA-targeting CRISPR systems, single-cell genomics, and high-throughput methods for protein engineering to tackle big questions in neurodegeneration, synthetic biology, gene &amp;amp; cell therapy, and beyond.&lt;/p&gt;
&lt;p&gt;Some of our ongoing projects and general interests include:&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Early-stage discovery and development of new genome, transcriptome, and epigenome engineering tools in mammalian cells (e.g. inventing new integrase systems for targeted insertion of large genetic payloads)&lt;/li&gt;
&lt;li&gt;Developing parts, sensors, and concepts for synthetic biology (e.g. engineering cell states, controlling or tracing cellular communication, development of therapeutic circuits, etc.)&lt;/li&gt;
&lt;li&gt;Applications of machine learning and protein language models to accelerate molecular technology parameters (efficiency, specificity, etc.)&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;About You&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;You are driven by science. The world of science is filled with so many unanswered questions and the opportunity to address these questions brings you purpose.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;You are a collaborator. You love working with people of different backgrounds and brainstorming ideas on how these questions can be addressed.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;You are curious. As much as you love answering questions, you also love creating/asking new ones.&amp;nbsp;&lt;/li&gt;
&lt;li&gt;You are an optimizer. In research, there’s always a race against the clock. You care deeply about making every step of the way as close to perfect as possible but also as quick and efficient as possible.&lt;/li&gt;
&lt;li&gt;You build tools. As much as you love answering specific scientific questions, you also love creating technology and platforms that are scalable and useful in many different scientific application areas.&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;In this position you will&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;Work as part of a fully funded team to invent, develop, and benchmark molecular technologies.&lt;/li&gt;
&lt;li&gt;Collaborate closely with the PIs on planning and executing scientific research projects.&lt;/li&gt;
&lt;li&gt;Lead key research projects while mentoring students and research assistants; provide guidance on project strategy, experimental design, data analysis, and troubleshooting.&lt;/li&gt;
&lt;li&gt;Keep up-to-date on advances in the field by reading the literature and attending key conferences.&lt;/li&gt;
&lt;li&gt;Develop and provide training to lab personnel as needed, develop standardized protocols for the labs.&lt;/li&gt;
&lt;li&gt;Assist with preparing manuscripts, abstracts, and presentations&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;strong&gt;Job requirements&lt;/strong&gt;&lt;/p&gt;
&lt;ul&gt;
&lt;li&gt;PhD and (optional) postdoctoral experience in a relevant life sciences or engineering field&lt;/li&gt;
&lt;li&gt;Experience with high-throughput molecular biology assays and techniques. Expertise in pooled library development is preferred.&lt;/li&gt;
&lt;li&gt;Mammalian cell line engineering experience&lt;/li&gt;
&lt;li&gt;Experience with NGS and flow cytometry techniques and data analysis&lt;/li&gt;
&lt;li&gt;Strong written and verbal communication skills is required for research presentations, preparing SOPs, and publications&lt;/li&gt;
&lt;li&gt;Experience and enthusiasm for mentoring research trainees, including graduate students and RAs&lt;/li&gt;
&lt;li&gt;The successful candidate will be an ambitious self-starter, be motivated to apply his/her skills to diverse projects and enjoy working in a collaborative and fast-paced team environment&lt;/li&gt;
&lt;/ul&gt;
&lt;p&gt;&lt;span style=&quot;font-weight: 400;&quot;&gt;The base salary range for this position is $112,500 to $148,500. These amounts reflect the range of base salary that the Institute reasonably would expect to pay a new hire or internal candidate for this position. The actual base compensation paid to any individual for this position may vary depending on factors such as experience, market conditions, education/training, skill level, and whether the compensation is internally equitable, and does not include bonuses, commissions, differential pay, other forms of compensation, or benefits. This position is also eligible to receive an annual discretionary bonus, with the amount dependent on individual and institute performance factors.&lt;/span&gt;&lt;/p&gt;

Working at the Arc Institute Solving hard science problems together

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Curiosity coupled with pragmatic solutions

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Open roles

Core Laboratories

Scientist/Sr. Scientist, Molecular Technology Development, Hsu & Konermann Lab

Palo Alto, CA

Operations

Information Technology Manager

Palo Alto, CA

Infrastructure Engineering Manager

Palo Alto, CA

Laboratory Operations Manager

Palo Alto, CA

People Team Coordinator

Palo Alto, CA

Scientific Recruiting Advisor

Palo Alto, CA

Technology Centers

Associate Director/Director of Bioinformatics

Palo Alto, CA

Associate Director, Functional Genomics

Palo Alto, CA

Director/Sr Director, Cellular Models Center

Palo Alto, CA

Scientist/Sr. Scientist, Functional Genomics, Genome Engineering Technology Center

Palo Alto, CA