iAnalyzer is an analytical pipeline designed for the robust analysis of CRISPR screens. It streamlines the processing of CRISPR screening data, facilitating tasks such as quality control, alignment, and statistical analysis to identify significant genetic perturbations.
Click here to access iAnalyzerHandles the entire workflow from raw data processing to result interpretation
Utilizes a metadata file to specify sample information, enhancing reproducibility and organization
Offers options to process data with or without Unique Molecular Identifiers (UMIs), accommodating various experimental designs
Currently supports Bowtie2 for sequence alignment, with provisions for integrating other aligners
Provides multiple options for combining z-scores, including sample size ('n'), standard error ('SE'), and standardized effect size ('SES')